NFL Week 15 odds, predictions, expert picks: Best bets, teasers, survivor picks, where to watch every game

As the NFL season heads into Week 15, playoff races are heating up, and every game matters. With marquee matchups, upset potential, and a mix of division rivalries, this week offers plenty of intrigue for fans and bettors alike. Below, we break down the odds, predictions, expert picks, and strategies to make the most of the week.

Game Previews and Predictions

Thursday Night Football

San Francisco 49ers (-7) vs. Seattle Seahawks

Time/TV: 8:15 PM ET, Prime Video
Prediction: 49ers 28, Seahawks 20
The 49ers are on a roll with one of the league’s most balanced rosters, while the Seahawks continue to struggle with defensive consistency. Brock Purdy and Christian McCaffrey should thrive against a porous Seahawks defense.

Saturday Tripleheader

Minnesota Vikings (-3.5) vs. Detroit Lions

Time/TV: 1:00 PM ET, NFL Network
Prediction: Lions 27, Vikings 24
The Lions are fighting for their playoff lives, and their offense, led by Jared Goff, has been firing on all cylinders. Expect Detroit to pull off the upset at home.

Buffalo Bills (-4.5) vs. Miami Dolphins

Time/TV: 4:30 PM ET, NFL Network
Prediction: Bills 31, Dolphins 27
Josh Allen and the Bills will look to avenge their early-season loss to Miami. In cold weather, Buffalo’s defense will make key stops late to secure the win.

Cleveland Browns (-2.5) vs. Baltimore Ravens

Time/TV: 8:15 PM ET, NFL Network
Prediction: Ravens 20, Browns 17
In a pivotal AFC North battle, Baltimore’s defense will carry the day, and Lamar Jackson’s mobility will create just enough offense to edge the Browns.

Sunday Slate

Philadelphia Eagles (-9) vs. Chicago Bears

Time/TV: 1:00 PM ET, FOX
Prediction: Eagles 34, Bears 21
The Eagles, led by MVP candidate Jalen Hurts, will have little trouble against a Bears team still searching for consistency. Philadelphia’s defense will stifle Justin Fields.

Dallas Cowboys (-10) vs. Jacksonville Jaguars

Time/TV: 1:00 PM ET, CBS
Prediction: Cowboys 27, Jaguars 24
Trevor Lawrence will keep the Jaguars in the game, but Dallas’s defense, led by Micah Parsons, will make critical plays late to preserve the win.

New York Jets (-2.5) vs. Detroit Lions

Time/TV: 1:00 PM ET, CBS
Prediction: Lions 23, Jets 20
The Lions continue their playoff push with a narrow victory over the Jets, thanks to a strong defensive effort and timely offense.

Kansas City Chiefs (-14) vs. Houston Texans

Time/TV: 1:00 PM ET, CBS
Prediction: Chiefs 38, Texans 14
Patrick Mahomes and the Chiefs will dominate from start to finish against a rebuilding Texans squad.

Pittsburgh Steelers (-3) vs. Carolina Panthers

Time/TV: 1:00 PM ET, FOX
Prediction: Steelers 21, Panthers 17
Pittsburgh’s defense will force multiple turnovers, and Kenny Pickett will manage the game effectively to lead the Steelers to victory.

New Orleans Saints (-5) vs. Atlanta Falcons

Time/TV: 1:00 PM ET, FOX
Prediction: Saints 24, Falcons 20
With playoff hopes still alive, New Orleans will take care of business behind a strong defensive showing and key plays from Alvin Kamara.

Denver Broncos (-1.5) vs. Arizona Cardinals

Time/TV: 4:05 PM ET, FOX
Prediction: Broncos 23, Cardinals 16
Denver’s defense will stifle Arizona, and Russell Wilson will deliver just enough offense to secure the win at home.

Las Vegas Raiders (-2) vs. New England Patriots

Time/TV: 4:25 PM ET, CBS
Prediction: Patriots 20, Raiders 17
In a clash of coaching philosophies, Bill Belichick’s defense will outwit the Raiders’ attack, leading to a low-scoring Patriots win.

Los Angeles Chargers (-3) vs. Tennessee Titans

Time/TV: 4:25 PM ET, CBS
Prediction: Chargers 30, Titans 27
Justin Herbert’s arm will be the difference in a shootout, as the Chargers keep their playoff hopes alive with a dramatic win.

Cincinnati Bengals (-4) vs. Tampa Bay Buccaneers

Time/TV: 4:25 PM ET, CBS
Prediction: Bengals 28, Buccaneers 21
Joe Burrow will outduel Tom Brady, and Cincinnati’s balanced attack will prove too much for Tampa Bay to handle.

Sunday Night Football

New York Giants (-1.5) vs. Washington Commanders

Time/TV: 8:20 PM ET, NBC
Prediction: Commanders 23, Giants 21
In a critical NFC East showdown, Washington’s defense will rise to the occasion, and rookie quarterback Jayden Daniels will make enough plays to outlast the Giants.

Monday Night Football

Green Bay Packers (-7) vs. Los Angeles Rams

Time/TV: 8:15 PM ET, ESPN
Prediction: Packers 27, Rams 17
The Packers will capitalize on a banged-up Rams team, with Aaron Rodgers leading the way to a comfortable victory at Lambeau Field.

Best Bets of the Week

Buffalo Bills (-4.5) vs. Dolphins: Buffalo is built for cold-weather games, and their superior defense gives them the edge in this high-stakes AFC East clash.
San Francisco 49ers (-7) vs. Seahawks: The 49ers’ dominant defense and versatile offense make them a strong pick to cover the spread.
Philadelphia Eagles (-9) vs. Bears: The Eagles’ dynamic offense should have no trouble dispatching the Bears.

Teasers of the Week

Teaser Option 1: Eagles (-9) teased to -3 and 49ers (-7) teased to -1
Teaser Option 2: Chiefs (-14) teased to -8 and Bills (-4.5) teased to +1

Survivor Picks

San Francisco 49ers: Facing a struggling Seahawks team, the 49ers are the safest survivor pick of the week.
Kansas City Chiefs: Against the Texans, the Chiefs are a near-lock to win outright.